Savory Pepperoni Pizza Biscuit Skillet in Just One Pan

There’s nothing like the thrilling moment when you pull a bubbling, cheesy Pepperoni Pizza Biscuit Skillet from the oven. The aroma wafts through the kitchen, pulling everyone in like a warm hug on a chilly evening. After a long day of work, I often find myself craving the comforts of pizza, but without the fuss of traditional dough-making. This easy one-pot meal comes to the rescue, ready in under an hour and packed with that irresistible pizza flavor.

Imagine flaky biscuit dough—so simple to work with—transformed into a delightful crust that cradles gooey mozzarella and savory pepperoni. Each bite is a perfect blend of warmth and satisfaction, making this dish a go-to for family dinners or casual get-togethers. Plus, the beauty of this recipe lies in its versatility. Feeling adventurous? Swap in your favorite toppings or cheese varieties, and let your creativity shine. Grab your skillet, and let’s dive into this delicious adventure together!

Why is the Pepperoni Pizza Biscuit Skillet irresistible?

Simplicity at Its Best: This recipe requires minimal ingredients and a single skillet, making cleanup a breeze.
Richly Flavorful: The combination of cheese, pepperoni, and fresh basil creates a tempting aroma that draws everyone to the table.
Time-Saving Delight: Whip it up in under an hour, perfect for those weekday dinners when time is tight.
Endless Variations: Mix and match toppings, from veggies to different cheeses, to please any palate, keeping your meals exciting.
Crowd-Pleasing Comfort: Nothing brings loved ones together like a warm, cheesy dish that feels like a hug on a plate.

Pepperoni Pizza Biscuit Skillet Ingredients

• Here’s everything you need to create your delicious meal!

For the Skillet

  • Cooking Spray – Helps prevent sticking; feel free to use any cooking oil you prefer.
  • Refrigerated Biscuit Dough (16.3 oz) – Delivers that flaky crust; you can swap in homemade or frozen dough as needed.
  • Pizza Sauce (15 oz) – Infuses moisture and flavor; marinara or any favorite pasta sauce works well as a substitute.

For the Toppings

  • Shredded Mozzarella (2 cups) – Offers the creamy, melty goodness that everyone loves; consider mixing it with provolone for extra flavor.
  • Pepperoni (3/4 cup total) – Adds a delightful pop of flavor; for a vegetarian version, use cooked sausage or a mix of vegetables instead.
  • Fresh Basil (2 Tbsp, plus more for serving) – Brightens up each bite with freshness; if you only have dried basil, that can work in a pinch, but fresh is always best.

How to Make Pepperoni Pizza Biscuit Skillet

  1. Preheat the oven to 375°F. This ensures that your skillet dish will bake evenly and come out perfectly golden brown.

  2. Prepare a 12″ skillet by spraying it with cooking spray. This helps to prevent sticking and makes serving easier.

  3. Cut each biscuit into six pieces. Toss them in a medium bowl with pizza sauce, mozzarella, and pepperoni until completely coated. This layering of flavors is what makes this dish so irresistible.

  4. Pour the biscuit mixture into the skillet. Bake it in the preheated oven for 40-45 minutes, or until the top is golden brown and the dough is cooked through. You want it to look deliciously bubbly!

  5. Garnish with fresh basil before serving. This adds a lovely touch of color and a burst of freshness to the dish.

Optional: Drizzle with olive oil for an extra punch of flavor.
Exact quantities are listed in the recipe card below.

Pepperoni Pizza Biscuit Skillet

What to Serve with Pepperoni Pizza Biscuit Skillet?

Nothing completes a cozy meal like the right sides to elevate your dining experience.

  • Garlic Breadsticks: Perfectly soft and buttery, they’re ideal for dipping into extra pizza sauce. A wonderful match that celebrates classic Italian flavors.

  • Caesar Salad: Crisp romaine tossed with tangy dressing and croutons provides a refreshing contrast to the rich and cheesy skillet.

  • Stuffed Bell Peppers: These colorful, healthy sides filled with quinoa and veggies add a vibrant, nutritious aspect to your meal. Their freshness complements the savory biscuit skillet beautifully.

  • Steamed Broccoli: Lightly steamed, drizzled with lemon, and seasoned with garlic, these florets bring brightness and nutrition to accompany your dish effortlessly.

  • Cola or Lemonade: These drinks balance the richness of the Pepperoni Pizza Biscuit Skillet, offering a fizzy or refreshing sip after each cheesy bite.

  • Chocolate Chip Cookies: A sweet finish to the meal, these warm cookies add a delightful touch for everyone, making it feel like a true feast.

Expert Tips for the Best Pepperoni Pizza Biscuit Skillet

  • Crispy Edges: Increase the oven temperature to 400°F for the last 10 minutes to achieve that golden, crispy edge everyone loves.

  • Prep Ahead: Chop the pepperoni and other toppings ahead of time. This saves you precious minutes and ensures an even distribution in your biscuit skillet.

  • Sauce Swap: If you prefer a different flavor, feel free to use your favorite brand of pizza sauce or even a homemade version. Just adjust the quantity based on taste preference!

  • Biscuit Alternatives: Don’t have refrigerated biscuit dough? Try using homemade or frozen dough—both work beautifully for this one-pot meal.

  • Top with Variety: Get creative! Mix in different cheeses or add veggies like bell peppers and onions. Each variation can create a unique Pepperoni Pizza Biscuit Skillet tailored to your family’s favorites.

Pepperoni Pizza Biscuit Skillet Variations

Feel free to get creative with this dish—customizing it can turn this recipe into an even more delightful experience!

  • Cheddar Kick: Swap mozzarella for sharp cheddar for a richer flavor that pairs beautifully with pepperoni.

  • Veggie Lovers: Replace pepperoni with a medley of bell peppers, mushrooms, and onions to make a vibrant vegetarian option. This twist adds a satisfying crunch and freshness.

  • Spicy Heat: Throw in sliced jalapeños or a sprinkle of red pepper flakes to spice things up. The heat complements the savory flavors beautifully.

  • Herb Infusion: Add a tablespoon of dried oregano or Italian seasoning to the biscuit mixture for a fragrant herb lift. This enhances the overall taste, giving it that pizzeria quality.

  • Garlic Butter Drizzle: Melt some garlic butter and drizzle it over the top before serving. It adds a mouthwatering richness that everyone will love.

  • Feta Surprise: Crumble feta cheese into the mix for a tangy twist. Its briny profile contrasts nicely with the other flavors, creating a delightful pairing.

  • BBQ Style: Substitute pizza sauce for barbecue sauce and mix in cooked chicken for a sweet and smoky version your family will adore.

  • Cheesy Layers: Opt for a blend of mozzarella and provolone for a gooey, stretchy texture that makes each bite blissful. You can’t go wrong with extra cheese!

How to Store and Freeze Pepperoni Pizza Biscuit Skillet

Fridge: Store any leftovers in an airtight container for up to 3 days. This keeps the flavors intact while maintaining the dish’s freshness.

Freezer: For longer storage, freeze the skillet meal in a tightly sealed container for up to 2 months. To prevent freezer burn, wrap it in plastic wrap before sealing.

Reheating: When ready to enjoy, thaw the frozen Pepperoni Pizza Biscuit Skillet in the fridge overnight. Reheat in the oven at 350°F for about 15-20 minutes, or until warmed through.

Serving Tip: Garnish with fresh basil right before serving to enhance the flavors and make the dish visually appealing!

Make Ahead Options

Preparing your Pepperoni Pizza Biscuit Skillet in advance is a fantastic way to save time during busy weeknights! You can chop the pepperoni and cut the biscuit dough up to 24 hours ahead and store them in the refrigerator in separate airtight containers. The pizza sauce and shredded mozzarella can also be measured and refrigerated to keep everything fresh. To maintain the quality of the dish, wait to combine all ingredients until just before baking. When it’s time to serve, simply mix the prepared components in your skillet and bake at 375°F for 40-45 minutes until bubbly and golden brown. With these handy prep steps, you’ll enjoy all the deliciousness with minimal effort!

Pepperoni Pizza Biscuit Skillet

Pepperoni Pizza Biscuit Skillet Recipe FAQs

What kind of biscuit dough should I use for the Pepperoni Pizza Biscuit Skillet?
I recommend using refrigerated biscuit dough for its flakiness and ease of use. However, if you’re feeling adventurous or have some on hand, homemade or frozen biscuit dough also works beautifully in this recipe!

How should I store leftovers of the Pepperoni Pizza Biscuit Skillet?
Store any leftover Pepperoni Pizza Biscuit Skillet in an airtight container in the fridge for up to 3 days. For best results, reheat it in the oven to restore that delightful crispy texture.

Can I freeze the Pepperoni Pizza Biscuit Skillet?
Absolutely! To freeze, place the completely cooled skillet meal in a tightly sealed container or wrap it in plastic wrap and then foil, ensuring it’s airtight. It can be frozen for up to 2 months. When you’re ready to enjoy, simply thaw it overnight in the fridge before reheating.

What if my biscuits don’t rise properly while baking?
If the biscuits don’t rise, it may be due to expired baking powder or biscuits that were packed too tightly in the skillet. Ensure you’re using fresh dough and layer it lightly for the best texture! An oven that’s too cool can also affect rising, so check that your preheat is accurate.

Can my pets enjoy the Pepperoni Pizza Biscuit Skillet?
While your furry friends might be intrigued by the aromas, it’s best not to share this dish with them. Pepperoni can be high in fat and sodium, which isn’t great, and the spices in pizza sauce may upset their stomach. Stick to pet-safe snacks for your beloved companions!

What’s a great way to customize the toppings for the Pepperoni Pizza Biscuit Skillet?
Get creative! You can mix in cooked crumbled sausage, sautéed bell peppers, mushrooms, or olives. If you prefer different cheeses, try cheddar or feta for a unique twist. The combination of flavors is endless—experiment until you find your favorite mix!

Pepperoni Pizza Biscuit Skillet

Savory Pepperoni Pizza Biscuit Skillet in Just One Pan

Enjoy this flavorful Pepperoni Pizza Biscuit Skillet, a comforting dish that combines biscuit dough with mozzarella and pepperoni for a delicious family meal.
Prep Time 15 minutes
Cook Time 45 minutes
Total Time 1 hour
Servings: 6 slices
Course: Dinner
Cuisine: Italian
Calories: 350

Ingredients
  

For the Skillet
  • 1 can Cooking Spray Helps prevent sticking; feel free to use any cooking oil you prefer.
  • 16.3 oz Refrigerated Biscuit Dough Delivers that flaky crust; homemade or frozen dough can be used.
  • 15 oz Pizza Sauce Infuses moisture and flavor; marinara can be substituted.
For the Toppings
  • 2 cups Shredded Mozzarella Offers creamy, melty goodness; mix with provolone for extra flavor.
  • 3/4 cup Pepperoni Adds flavor; can substitute with cooked sausage or veggies for a vegetarian version.
  • 2 Tbsp Fresh Basil Brightens up each bite; dried basil can work, but fresh is best.

Equipment

  • 12-inch skillet

Method
 

Steps
  1. Preheat the oven to 375°F.
  2. Prepare a 12" skillet by spraying it with cooking spray.
  3. Cut each biscuit into six pieces and toss them with pizza sauce, mozzarella, and pepperoni.
  4. Pour the biscuit mixture into the skillet and bake for 40-45 minutes.
  5. Garnish with fresh basil before serving.

Nutrition

Serving: 1sliceCalories: 350kcalCarbohydrates: 30gProtein: 15gFat: 22gSaturated Fat: 9gPolyunsaturated Fat: 1gMonounsaturated Fat: 10gCholesterol: 50mgSodium: 800mgPotassium: 300mgFiber: 2gSugar: 4gVitamin A: 10IUVitamin C: 5mgCalcium: 20mgIron: 15mg

Notes

Optional: Drizzle with olive oil for extra flavor. Prep ahead by chopping toppings to save time.

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